3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane and benztropine

3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane has been researched along with benztropine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, AC; George, C; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH1
Allen, AC; Izenwasser, S; Katz, JL; Newman, AH1
Bowen, WD; Izenwasser, S; Joseph, DB; Katz, JL; Kline, RH; Newman, AH1
Izenwasser, S; Kline, RH; Newman, AH; Robarge, MJ1
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH1

Other Studies

5 other study(ies) available for 3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane and benztropine

ArticleYear
Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes

1995
Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Dopamine Antagonists; Mice; Rats; Structure-Activity Relationship; Tropanes

1994
3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Animals; Benztropine; Binding, Competitive; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Neostriatum; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tropanes

1997
CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Animals; Binding Sites; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Tropanes

1999
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software

2000